MIT scientists discover how the brain spins back into focus-Click HereSunflowers may be the future of “vegan meat”-Click HereAlzheimer’s might be powered by a broken sleep-wake cycle-Click HereBreakthrough blood test finally confirms Chronic Fatigue Syndrome-Click HereGum disease may quietly damage the brain, scientists warn-Click HereScientists reverse Alzheimer’s in mice with groundbreaking nanotech-Click HereIt sounds creepy, but these scientific breakthroughs could save lives-Click HereYour pumpkin might be hiding a toxic secret-Click HereA revolutionary DNA search engine is speeding up genetic discovery-Click HereWhy women live longer than men, explained by evolution-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Testosterone Gel: Hope After Hip Fractures

0

ST LOUIS, Mo. (Ivanhoe Newswire) — Every 11 seconds, an older adult is treated in the emergency room for a fall, and every 19 minutes, an older adult dies from one. Doctors are trying to improve those statistics. They’re testing weight-lifting and testosterone gel supplements to give women who break a hip a better shot at a full recovery,

Joan Mowery hits the gym twice a week.

It’s all part of her recovery from a broken hip.

Mowery said, “I might be 79 physically, but mentally, I’m not, and you know, no, this ain’t gonna stop me.”

Each year, 300,000 Americans break a hip. Seventy-five percent never get back to the function they had before the fractur

“When I saw the statistics, I was horrified. I really was. Seventy-five percent? That’s outrageous,” said Mowery.

But that’s not the only grim statistic.

“A significant number of patients do not survive after the hip fracture. There’s about a 25 percent mortality rate within the first year,” said Ellen Binder, MD, a Geriatrician at Washington University in St. Louis.

(Read Full Interview)

Dr. Binder is testing a testosterone supplement with an extended weight-lifting program to improve those odds for women.

“They are getting better. And they are getting stronger,” Dr. Binder said.

Testosterone increases muscle and bone mass. Women use the gel once a day and lift weights twice a week for six months. A pilot study shows this approach improves mobility, lean body mass and strength.

“The functional aspect of this is really the muscles getting stronger; the walking getting better; the balance getting better,” Dr. Binder told Ivanhoe.

Mowery has already seen the benefit.

“Not only am I improving on the side that was fractured. I’m improving all the way around,” said Mowery.

She plans to join her own gym when the study is over. There’s no chance she’ll let herself become a statistic.

“I got too much to do. I’m not done,” Mowery shared.

On average, most people will get about three weeks of inpatient rehab after a hip fracture, depending on their insurance, followed by a few weeks at home. The rehab program in this study is six full months. Doctors hope that extended rehab will get women back to their old selves and reduce the risk of future fractures. The study is still recruiting patients in St. Louis, Denver, Boston, Baltimore, Galveston, Texas and Farmington, Connecticut.

Contributors to this news report include: Stacie Overton Johnson, Field Producer; Rusty Reed, Videographer; Cyndy McGrath, Supervising Producer; Jamison Kozcan, Editor.

To receive a free weekly e-mail on Medical Breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

 

TOPIC:            TESTOSTERONE GEL GIVES WOMEN HOPE AFTER HIP FRACTURES

REPORT:       MB #4633

BACKGROUND: Hip fractures most commonly occur from a fall or from a direct blow to the side of the hip. Some medical conditions such as osteoporosis, cancer, or stress injuries can weaken the bone and make the hip more susceptible to breaking. In severe cases, it is possible for the hip to break with the patient merely standing on the leg and twisting. Patients may be encouraged to get out of bed on the day following surgery with the assistance of a physical therapist. The amount of weight that is allowed on the injured leg will be determined by the surgeon and is generally a function of the type of fracture and repair.

(Source: https://orthoinfo.aaos.org/en/diseases–conditions/hip-fractures)

RECOVERY: A hip fracture can change the rest of a patient’s life, even after surgery and rehabilitation. According to the AARP, the year after fracturing a hip, 90 percent of those who needed no assistance climbing stairs before the fracture will not be able to climb five stairs; 66 percent won’t be able to get on or off a toilet without help; 50 percent won’t be able to raise themselves from a chair; 31 percent won’t be able to get out of bed unassisted; and 20 percent won’t be able to put on a pair of pants by themselves. Researchers are trying to change some of these statistics.

(Source: https://www.aarp.org/health/conditions-treatments/info-10-2011/hip-fractures-survival.html)

NEW RESEARCH: Ellen Binder, MD, a Geriatrician at Washington University in St. Louis said, “Many years ago we did a large clinical trial looking at whether intensive and extended exercise in hip fracture patients would be beneficial relative to their mobility and their ability to do activities of daily living. And we demonstrated that compared to the usual kinds of exercises that patients do after they’ve finished their standard physical therapy that those that did intensive exercise that included weight training gained much more mobility and strength and ability to do activities of daily living.” With a new study, Dr. Binder is looking at using testosterone combined with exercise, “We actually know from the world of sports where people have been using steroids for many years that it does enhance performance. And we think it’s important to evaluate in women and particularly in women who are in a very weakened condition to see whether this can help to enhance their rehabilitation and essentially help jump start in conjunction with how quickly they recover.”

(Source: Ellen Binder, MD)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

Judy Martin Finch, PR

314-286-0105

martinju@wustl.ed

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Ellen Binder, MD, a Geriatrician

Read the entire Q&A