A revolutionary DNA search engine is speeding up genetic discovery-Click HereWhy women live longer than men, explained by evolution-Click HereBananas could be ruining your smoothie’s health benefits-Click HereThis easy daily habit cuts heart risk by two thirds-Click HereWeight-loss drugs like Ozempic may also curb drug and alcohol addiction-Click HereLife expectancy gains have slowed sharply, study finds-Click HereHow strong is your weed, really? Scientists say labels often mislead-Click HereMIT scientists discover hidden 3D genome loops that survive cell division-Click HereYou might look healthy, but hidden fat could be silently damaging your heart-Click HereScientists reversed brain aging and memory loss in mice-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Irregular Sleep Deadly for the Heart

0

NASHVILLE, Tenn. (Ivanhoe Newswire) – Lack of sleep is overall bad for health, but a recent study shows us that the consequences can be worse than we thought. Chronically disrupted sleep can trigger heart disease and dementia. Sleeping less than six hours a night increases heart attack risk by 20 percent, as researchers discovered in a recent Vanderbilt study.

Tossing and turning at night is more than just annoying – poor sleep triggers cardiovascular issues by plugging arteries with dangerous plaque, and causing them to stiffen.

Kelsie Full, PhD, MPH, Assistant Professor of Medicine in the Division of Epidemiology at the Vanderbilt University Medical Center, explains, “Poor sleep can alter the regulation of hormones, it can cause increased inflammation.”

(Read Full Interview)

This causes fatty plaque buildup in arteries that can cause stroke. Simultaneously, blood pressure soars, oxygen goes down, and the body is prevented from cleansing and repairing itself.

“For the brain, sleep is the time when the brain is flushed of harmful toxins that can contribute to Alzheimer’s and dementia,” Professor Full adds.

The key to making this happen is getting good quality, consistent sleep, but many people suffer with irregular sleep patterns.

Professor Full says, “In our large sample, we found that approximately 40% of adults had irregular sleep patterns, and their sleep was varying across the week by about 90 minutes or more. And this is really important because sleep regularity is something that we can potentially target. So, we can try to have more consistent bedtimes, we can try to wake up at about the same time.”

Professor Full suggests effective sleep hygiene by minimizing light, lowering the thermostat and avoiding caffeine and stress. Finally, keep a sleep journal for 10 days. If you realize you’re short on sleep, see your doctor.

Sleep requirements vary by age, with infants needing 12 to 16 hours and older adults only requiring seven – an estimated 83.6 million Americans sleep fewer than that. Factors such as obesity, chronic illness, even where you live, has an impact.

Contributors to this news report include: Donna Parker, Producer; Roque Correa, Videographer & Editor.

To receive a free weekly e-mail on medical breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

Sources:

https://www.sleepfoundation.org

cdc.gov

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

TOPIC:            IRREGULAR SLEEP DEADLY FOR THE HEART

REPORT:        MB #5286

BACKGROUND: Poor sleep can negatively affect your heart health. According to the CDC, adults require at least seven hours of sleep, but about one in three Americans don’t get an adequate amount of sleep per night. Poor sleep can lead to high blood pressure, type 2 diabetes, obesity, heart attacks, and stroke. The two most common reasons for poor sleep are sleep apnea and insomnia.

(Sources: https://www.cdc.gov/bloodpressure/sleep.htm#:~:text=Insomnia%20is%20linked%20to%20high,especially%20earlier%20in%20the%20day.

https://www.sleepfoundation.org/sleep-deprivation/how-sleep-deprivation-affects-your-heart)

DIAGNOSING: Some signs and symptoms that you didn’t get enough sleep are: daytime sleepiness, fatigue, irritability, slowed reaction times, and/or headaches. Some symptoms of sleep apnea are similar to not getting enough sleep, but they also include: loud snoring, waking in the middle of the night gasping for air or choking, mood changes, and/or high blood pressure. Some signs of insomnia are: difficulty falling asleep at night, waking up too early, difficulty paying attention, and/or ongoing worries about sleep. Doctors can diagnose these issues with sleep apnea testing, an EEG, actigraphy, a multiple sleep latency test (or MSLT), or a maintenance of wakefulness test (or MWT).

(Sources: https://my.clevelandclinic.org/health/diseases/23970-sleep-deprivation

https://www.mayoclinic.org/diseases-conditions/obstructive-sleep-apnea/symptoms-causes/syc-20352090

https://www.mayoclinic.org/diseases-conditions/insomnia/symptoms-causes/syc-20355167

NEW TECHNOLOGY: If it seems like the natural remedies or over-the-counter drugs aren’t working, fret not. The FDA approved Daridorexant, a drug that could treat poor sleep. According to the National Library of Medicine, “Daridorexant is a dual orexin type 1 and types 2 receptor antagonist that was recently approved by the US FDA for the treatment of adults suffering from insomnia. It was shown to be effective in reducing insomnia symptoms, increasing daytime functioning, and improving the overall quality of sleep. Daridorexant offers patients relief from insomnia while avoiding the severe side effects and dependency issues of traditional treatments like benzodiazepines and sedatives.”

(Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9425279/#:~:text=Daridorexant%20was%20patented%20in%202013,US%20on%20January%207%2C%202022.&text=It%20is%20available%20in%2025%20to%2050%20mg%20once%20daily%20oral%20doses.)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

Craig Boerner

Craig.boerner@vumc.org

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Kelsie Full, Assistant Professor of Medicine in the Division of Epidemiology

Read the entire Q&A