A revolutionary DNA search engine is speeding up genetic discovery-Click HereWhy women live longer than men, explained by evolution-Click HereBananas could be ruining your smoothie’s health benefits-Click HereThis easy daily habit cuts heart risk by two thirds-Click HereWeight-loss drugs like Ozempic may also curb drug and alcohol addiction-Click HereLife expectancy gains have slowed sharply, study finds-Click HereHow strong is your weed, really? Scientists say labels often mislead-Click HereMIT scientists discover hidden 3D genome loops that survive cell division-Click HereYou might look healthy, but hidden fat could be silently damaging your heart-Click HereScientists reversed brain aging and memory loss in mice-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Esophageal Cancer

0

NEW YORK, N.Y. (Ivanhoe Newswire) – Esophageal cancer is cancer of the long tube that runs from the throat to the stomach. Traditionally, the treatment involves surgery but afterwards, there is a risk of the esophagus leaking, which could cause dangerous, even potentially fatal infections. Now, surgeons at Mount Sinai in New York have pioneered a modification that significantly cuts the risk.

Lou Martinez collects coins, clocks, and other knick knacks. He loves things that have a long history. But in 2018, Martinez’s health took a turn – he was working nights and had a sudden, serious scare.

“I couldn’t swallow my food. I couldn’t swallow water, juice, nothing. Everything laid right there, and I panicked,” Martinez painfully recalls.

After years of struggling with heartburn, doctors diagnosed Martinez with esophageal cancer.

Patients can have complications at the site where surgeons reconnect the esophagus and stomach.

“And that needs to heal. And when that doesn’t heal, the contents leak out. A leak can be out of control where the patient is sick. Sepsis can potentially lead to death,” explains Mount Sinai Chief of Thoracic Surgery, Dr. Raja Flores.

(Read Full Interview)

Dr. Flores and his colleagues have revised the procedure in a way that maximizes good blood flow to the area.

“We figured out that you can do the operation without cutting that right gastric artery. And it’s not just the artery, but it’s the vein. You wanna make sure you keep everything intact,” Dr. Flores further explains.

The revised surgery lowers the complication rate from 25 percent of the patients to just under two percent.

At first, Martinez was afraid to have surgery, but Dr. Flores convinced him it would be lifesaving. Now, that he’s recovered, Martinez says unlike the antiques he collects, these days, he feels brand new.

Dr. Flores says the new technique also decreases surgical time from seven hours to two and a half. He says it’s important for patients to know that a heartburn, and acid reflux, fueled by an increase in obesity, can be life-threatening if not addressed.

Contributors to this news report include: Cyndy McGrath, Producer; Kirk Manson, Videographer; Roque Correa, Editor.

To receive a free weekly e-mail on medical breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

Source:

https://www.cancer.org/cancer/esophagus-cancer/causes-risks-prevention/risk-factors.html

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

TOPIC:            ESOPHAGEAL CANCER: NEW SURGICAL INNOVATION STOPS RISKY SIDE EFFECTS

REPORT:       MB #5167

BACKGROUND: Esophageal cancer is a disease in which malignant cells form in the tissues of the esophagus, which is a long, hollow tube that runs from your throat to your stomach. Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Incidence rates vary within different geographic locations. In some regions, higher rates of esophageal cancer may be attributed to tobacco and alcohol use or particular nutritional habits and obesity. About 20,640 new esophageal cancer cases are diagnosed every year in the United States and there are about 16,410 deaths from esophageal cancer.

(Sources: https://www.cancer.gov/types/esophageal/patient/esophageal-treatment-pdq#:~:text=Esophageal%20cancer%20is%20a%20disease,and%20painful%20or%20difficult%20swallowing.

https://www.mayoclinic.org/diseases-conditions/esophageal-cancer/symptoms-causes/syc-20356084

https://www.cancer.org/cancer/esophagus-cancer/about/key-statistics.html)

DIAGNOSING: Unfortunately, most esophageal cancers do not cause symptoms until they have reached an advanced stage, when they are harder to treat. But the most common symptoms of esophageal cancer are trouble swallowing, chest pain, weight loss, hoarseness, chronic cough, vomiting, bone pain, and/or bleeding into the esophagus. Having one or more symptoms does not mean you have esophageal cancer. In fact, many of these symptoms are more likely to be caused by other conditions. Still, if you have any of these symptoms, especially trouble swallowing, it’s important to have them checked by a doctor so that the cause can be found and treated, if needed.

(Source: https://www.cancer.org/cancer/esophagus-cancer/detection-diagnosis-staging/signs-and-symptoms.html)

NEW TECHNOLOGY: Typically, esophageal cancer — either squamous cell esophageal cancer or adenocarcinoma — is treated with a combination of chemotherapy, radiation and surgery to remove the tumor from the esophagus. The patient’s tumor will be examined to see whether there is residual cancer left in the sample specimen; if there is, patients have a higher risk of a relapse or recurrence. In the United States, adenocarcinomas, which begin in the gland cells in the lower third of the esophagus, are the most common type of esophageal cancer. Risk factors include a history of acid reflux or gastroesophageal reflux disease (GERD). Worldwide, however, squamous cell carcinoma, which begins in the squamous cells of the esophageal lining, is more common. Risk factors include a history of smoking, alcohol consumption and poor oral hygiene. New immunotherapies present new options for both types of esophageal cancer. The next front in this research is to determine how to make immunotherapies work even better. This is where Roswell Park researchers like Dr. Sarbajit Mukherjee and his team are focusing and why he encourages his patients and their families to consider enrolling in clinical trials for new treatments.

(Source: https://www.roswellpark.org/cancertalk/202110/new-immunotherapy-based-treatments-esophageal-cancer-show-promise)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

Marlene Naanes

(919) 273-5802

Marlene.naanes@mountsinai.org

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Dr. Raja Flores, MD, Chief of Thoracic Surgery

Read the entire Q&A