How strong is your weed, really? Scientists say labels often mislead-Click HereMIT scientists discover hidden 3D genome loops that survive cell division-Click HereYou might look healthy, but hidden fat could be silently damaging your heart-Click HereScientists reversed brain aging and memory loss in mice-Click HereDoctors just found a way to slow one of the deadliest prostate cancers-Click HereRunning fixes what junk food breaks in the brain-Click HereBird flu hiding in cheese? The surprising new discovery-Click HereHow just minutes of running can supercharge your health-Click HereScientists reveal the best exercise to ease knee arthritis pain-Click HereAre cancer surgeries removing the body’s secret weapon against cancer?-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Better Breathing with COPD

0

CINCINNATI, Ohio (Ivanhoe Newswire) – About 12.5 million Americans have chronic obstructive pulmonary disease, or COPD. With COPD, less air flows in and out of the airways. The tiny air sacs in the lungs are damaged, and unable to stretch and shrink. Now, a team of physician-scientists have developed a non-invasive device that can help patients with their breathing.

University of Cincinnati College of Medicine pulmonologist, Ralph Panos, MD explains, “The main cause of breathlessness in COPD is something called air trapping, or dynamic hyperinflation. It’s an inability to exhale all of the air that one takes in.”

(Read Full Interview)

Treatments include a rescue inhaler and steroids. Patients are also taught to practice a special method of breathing.

Dr. Panos says, “They learned something called pursed lip breathing, which is breathing out through pursed lips to create that back pressure.”

Dr. Panos and his colleagues developed a hands-free device that helps patients simulate pursed lip breathing. The device is called the positive expiratory pressure, or PEP Buddy.

“It’s just simply placed in the mouth, one breathes in through the nose, and then out through the device. That resistance to airflow creates the back pressure, which relieves the air trapping and dynamic hyperinflation,” Dr. Panos demonstrates.

The researchers say there are many benefits of slow breathing and exhalation. Now, a tiny tool can help.

Dr. Panos and his colleagues developed the PEP Buddy with help from a University of Cincinnati department that provides a launchpad for entrepreneurs. The researchers are in the process of obtaining what’s called class one approval from the FDA, which is for medical devices that are considered low risk for consumer use. Since the device is considered low risk, it can be available for purchase before it gets FDA-approval. The PEP Buddy is currently being sold for $25 and is not covered by insurance.

Contributors to this news report include: Cyndy McGrath, Producer; Kirk Manson, Videographer; Roque Correa, Editor.

To receive a free weekly e-mail on medical breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

Sources:

https://www.lung.org/lung-health-diseases/lung-disease-lookup/copd/learn-about-copd#:~:text=COPD%20affects%2012.5%20million%20adults,of%20the%20burden%20of%20COPD.

https://jamanetwork.com/journals/jama/fullarticle/1817798#:~:text=Class%20I%20devices%20are%20low,infusion%20pumps%20for%20intravenous%20medications.

Dr. Ralph Panos

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

TOPIC:            PEP BUDDY: BETTER BREATHING WITH COPD

REPORT:       MB #5222

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease that makes it difficult for individuals to breathe. It can also be called chronic bronchitis or emphysema. COPD is characterized by long-term damage to the airways, which results in the limitation of airflow to and from the lungs. The primary cause of COPD is exposure to harmful substances such as cigarette smoke, air pollution, and occupational dust and chemicals. Individuals with a history of smoking are at a higher risk of developing COPD than non-smokers. Other risk factors include age, genetic factors, and a history of lung infections. About 12.5 million Americans are living with chronic obstructive pulmonary disease.

(Sources: https://www.who.int/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd)

https://www.lung.org/lung-health-diseases/lung-disease-lookup/copd/learn-about-copd#:~:text=COPD%20affects%2012.5%20million%20adults,of%20the%20burden%20of%20COPD)

DIAGNOSING: The symptoms of COPD include coughing, wheezing, shortness of breath, and chest tightness. In the early stages of the disease, these symptoms may be mild and go unnoticed, but as the disease progresses, they can become more severe and debilitating. There is no cure for COPD, but treatment options are available to manage the symptoms and slow the progression of the disease. Medications such as bronchodilators, corticosteroids, and antibiotics may be prescribed to relieve symptoms and prevent exacerbations. COPD is a leading cause of morbidity and mortality worldwide, and it is estimated that more than 251 million people are affected by this disease. Early diagnosis and treatment can improve outcomes and quality of life for those with COPD, and ongoing research is focused on developing new therapies to further improve management of this chronic disease.

(Sources: https://metone.com/chronic-obstructive-pulmonary-disease-copd-awareness-month-november-2021-5-actionable-goals-to-combat-this-condition/

https://www.copdfoundation.org/What-is-COPD/Understanding-COPD/How-is-COPD-Diagnosed.aspx?gclid=CjwKCAjwov6hBhBsEiwAvrvN6H8NlxhyM0kqVYEvQccH92nSLrEIrigV3R0BaWRq9TQcyQuVdt1yWhoCvpYQAvD_BwE)

NEW TECHNOLOGY: Ralph J. Panos, MD is a respiratory physician who developed, along with his colleagues, the Positive-Expiratory Pressure (PEP) device to help individuals with respiratory conditions such as chronic obstructive pulmonary disease, cystic fibrosis, chronic bronchitis, and bronchiectasis to clear their airways. The PEP device creates resistance against the air flow during exhalation, which helps to keep the airways open and promote the removal of mucus from the lungs. The device is usually a small handheld plastic device with a mouthpiece that is attached to a resistance valve.

(Sources: https://www.hpnonline.com/surgical-critical-care/article/53028226/researchers-develop-handsfree-breathing-aid-for-copd

https://www.sciencedaily.com/releases/2023/03/230310123846.htm)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

Tim Tedeschi

tedesctd@ucmail.uc.edu

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Dr. Ralph Panos, Pulmonologist

Read the entire Q&A