They found the switch that makes the body attack cancer-Click HereThis common liver supplement could boost cancer treatment success-Click HereThis European treatment for joint pain just passed a major scientific test-Click HereTiny brain nanotubes found by Johns Hopkins may spread Alzheimer’s-Click HereExercise might be the key to a younger, sharper immune system-Click HereScientists grow mini human livers that predict toxic drug reactions-Click HereThis new blood test can catch cancer 10 years early-Click HereYour brain’s power supply may hold the key to mental illness-Click HereNew research reveals how ADHD sparks extraordinary creativity-Click HereThis experimental “super vaccine” stopped cancer cold in the lab-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Back Pain Paradox

0

ORLANDO, Fla. (Ivanhoe Newswire) — It’s been called the painkiller paradox: millions of Americans are suffering from chronic pain, especially back pain, and need medication to make it manageable. On the other hand, many say they’ve gotten hooked on those same drugs designed to help. Now researchers are looking at safer solutions that may help avoid the high toll of addiction.

Thirty-eight-year-old Chrioni Lenertz has experienced a lot in her lifetime – from traveling the world as a merchant marine, to surviving stage 4 breast cancer. She overcame every challenge … until injuring her back in the gym.

“I’m a young person I’m an active person and so I want to still continue, especially being a cancer survivor,” said Lenertz.

But Lenertz didn’t want to take pain pills for her back and experts say for many people, there’s good reason.

“Those people who tend to go down the path of utilizing opioids have a hard time kind of riding that ship and going in the other direction,” said William J. Hanney, DPT, PhD, ATC, CSCS, Associate Professor of Physical Therapy at the University of Central Florida.

Professor Albert Lui studies health informatics.  He looked at the numbers for 45,000 with acute low back pain and followed them for a year.   The patients who started physical therapy within three days of being evaluated had fewer ER visits, were less likely to seek out advanced imaging, and …

“They were ten to 15 percent less likely to use a pain medication over one year,” said Xinliang “Albert” Liu, PhD, Assistant Professor in the Department of Health Management and Informatics at the University of Central Florida.

(Read Full Interview)

Researchers also say immediate referral could lead to huge savings each year.

“We can achieve a cost saving of seven billion dollars nationwide,” Liu told Ivanhoe

Lenertz saw her doctor and now manages her pain through yoga and exercise.

“And I can just enjoy things a little bit more and not be so rough on myself,” she said.

In addition to physical therapy, researchers nationwide are working to find non-opioid drug treatments. The FDA recently fast-tracked the drug tanezumab to treat chronic back pain.

Contributors to this news report include: Cyndy McGrath, Supervising Producer; Hayley Hudson, Assistant Producer; Roque Correa, Videographer; Dave Harrison, Editor.

To receive a free weekly e-mail on Medical Breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

 

TOPIC:            BACK PAIN PARADOX

REPORT:       MB #4492

 BACKGROUND: Back pain is one of the most common medical problems, affecting eight out of 10 people at some point during their lives. Back pain can range from a dull, constant ache to a sudden, sharp pain. Acute back pain comes on suddenly and usually lasts from a few days to a few weeks. Back pain is called chronic if it lasts for more than three months. Most back pain goes away on its own, though it may take time. Taking over-the-counter pain relievers and resting can help. However, staying in bed for more than one or two days can make it worse. Treatment for back pain depends on what kind of pain you have, and what is causing it. It may include hot or cold packs, exercise, medicines, injections, complementary treatments, and sometimes surgery.

(Source: https://medlineplus.gov/backpain.html)

OPIOIDS: The most common prescription drug in U.S. adults with chronic low back pain (LBP) are opioids, according to a population study based on the 2009 to 2010 National Health and Nutrition Examination Survey. Opioids in this population were found to be used long-term and in combination with other central nervous system-acting agents. The majority (76.9%) of individuals with chronic LBP taking opioids reported taking opioids for more than one year. Duration of prescription medication use was greater in participants with, rather than without chronic LBP for opioids, acetaminophen, NSAIDs, and muscle relaxants. Opioid medications were commonly taken with antidepressants, benzodiazepines, or hypnotics. In addition, the majority (94%) of participants with chronic LBP who used prescription opioids did not have a college education, and a greater percentage of women vs men with chronic LBP used nonsteroidal anti-inflammatory drugs and muscle relaxants.

(Source: https://www.clinicalpainadvisor.com/low-back-pain/opioid-long-term-use-demographics-chronic-low-back-pain/article/766079/)

NEW RESEARCH: A research team led by the University of Central Florida has evaluated how the use of physical therapy to treat acute low back pain ― and the timing of when treatment begins ― impact the use and costs of health care. Patients with immediate treatment, about 27 percent, were the least likely to have emergency room visits. Nearly 33 percent of patients who had no physical therapy used emergency room services. Patients with immediate treatment also were the least likely to fill a prescription for opioid medication (44 percent), followed by patients receiving no physical therapy (48 percent), patients receiving therapy 4-14 days later (54 percent) or 15-28 days later (61 percent).

(Source: https://today.ucf.edu/back-pain-treatment-costs-opioid-use-drop-when-patients-seek-immediate-care/)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

Megan Pabian, PR

407-276-6607

megan.pabian@ucf.edu

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Xinliang “Albert” Liu, PhD, Assistant Professor, Department of Health Management and Informatics

Read the entire Q&A