How strong is your weed, really? Scientists say labels often mislead-Click HereMIT scientists discover hidden 3D genome loops that survive cell division-Click HereYou might look healthy, but hidden fat could be silently damaging your heart-Click HereScientists reversed brain aging and memory loss in mice-Click HereDoctors just found a way to slow one of the deadliest prostate cancers-Click HereRunning fixes what junk food breaks in the brain-Click HereBird flu hiding in cheese? The surprising new discovery-Click HereHow just minutes of running can supercharge your health-Click HereScientists reveal the best exercise to ease knee arthritis pain-Click HereAre cancer surgeries removing the body’s secret weapon against cancer?-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Appendicitis: Antibiotics Treat

0

SEATTLE, Wash. (Ivanhoe Newswire)— About 300,000 Americans get their appendix removed each year due to illness. But a new study reveals there may be an alternative to going under the knife. Appendicitis

What if you had the option between having surgery or taking a pill to treat an illness?

“For me, the idea of not having to have myself cut open in any way shape or form is attractive,” shared patient advocate Bonnie Bizzell.

A new University of Washington study finds antibiotics may be an alternative for patients suffering from appendicitis. Historically, the first line of treatment has been surgery to remove the appendix. But …

“With COVID, it had really changed how healthcare systems were taking care of patients, and really wanting to minimize exposure,” explained Giana Davidson, MD, MPH, associate professor of surgery at the University of Washington School of Medicine.

When doctors compared patients who had an appendectomy right away versus those who took antibiotics, they found both groups had similar outcomes for length of time in the hospital and recovery 30 days out. Experts say this research provides patients with a choice when it comes to treatment.

“There are times in my life when having surgery would not have been a good option for me,” Bizzell recalled.

Dr. Davidson described, “We really had patients at the center, saying the things that were important to them to look for? Is it time off work, you need to be a caregiver, is it that you have finals coming up?”

But choosing antibiotics instead of surgery is not without risk. Some patients in the antibiotic group did have to return to the emergency room a few days later and three out of ten patients from the antibiotics group eventually went on to have an appendectomy within 90 days. But most recovered without surgery.

“I think that changes the whole experience,” Bizzell concluded.

Patients with a burst appendix were also included in the trial. Dr. Davidson says those patients don’t necessarily have to be rushed to surgery and may be treated with a ten-day course of antibiotics. But future research is needed to evaluate the risk factors.

Contributors to this news report include: Cyndy McGrath, Executive Producer; Milvionne Chery, Field Producer; Rusty Reed, Videographer; Roque Correa, Editor.

To receive a free weekly e-mail on Medical Breakthroughs from Ivanhoe, sign up at: http://www.ivanhoe.com/ftk

Sources:

https://www.livescience.com/63699-appendicitis-antibiotics.html

MEDICAL BREAKTHROUGHS

RESEARCH SUMMARY

 

TOPIC:            ANTIBIOTICS TREAT APPENDICITIS: NO SURGERY NEEDED!

REPORT:       MB #4876

BACKGROUND: The appendix is an organ the size of a finger-shaped pouch that protrudes from the colon in the lower right quadrant of the abdomen. Appendicitis occurs when the appendix becomes inflamed and causes severe pain in the lower right abdomen that typically increases. Most patients report pain beginning at the belly button and the moving to their side as the appendicitis progressed. Anyone is capable of developing appendicitis, it most often occurs in children as young as ten all the way to adults. Signs or symptoms of appendicitis include sudden abdominal pain, pain that worsens when coughing, walking, or making sudden movements, nausea and vomiting, loss of appetite, low-grade fever that may worsen, constipation or diarrhea and abdominal bloating. A blockage of the lining of the appendix resulting in infection is the most common cause of appendicitis. If appendicitis is not treated promptly the appendix will burst. A ruptured appendix spreads infection throughout your abdomen and can be life threatening.

(Source: https://www.mayoclinic.org/diseases-conditions/appendicitis/symptoms-causes/syc-20369543)

TREATMENT: The traditional treatment for appendicitis, and other appendix-related issues, is appendectomy, or surgical removal of the appendix. There are two types of surgical procedures to remove the appendix, open or laparoscopic. The traditional method is open appendectomy, cutting a two-to-four-inch incision into the lower right abdomen and then removing the appendix through that incision. A newer, minimally invasive option is laparoscopic appendectomy where, instead of a large incision, one to three tiny cuts are made and a long thin tube called a laparoscope is put into one of the incisions, it has a tiny video camera and surgical tools that a surgeon can view and operate by looking at a monitor. The appendix is removed through one of these small incisions. During a laparoscopic surgery, surgeons still may decide that an open appendectomy is needed, especially if the appendix has burst and infection has spread.

(Source: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/appendectomy#:~:text=If%20you%20have%20appendicitis%2C%20your,surgery%20to%20remove%20the%20appendix.)

NEW TECHNOLOGY: A new study looked at 250 adults in Finland who had appendicitis and were treated with antibiotics instead of surgery. This group was then compared to another group of 270 adults who had surgery for appendicitis. The study followed all participants for five years. By the end of the study, nearly two-thirds, or 64 percent, of the people in the antibiotic group

were considered “successfully treated,” meaning they didn’t have another appendicitis attack and their appendix did not burst. The other 36 percent in the antibiotic group eventually needed to have surgery to remove their appendix. However, these participants experienced no harmful outcomes due to the delay caused by antibiotic treatment. The antibiotic group also had much lower rates for complication and shorter recovery time when compared to those who had surgery, with most patients returning to work or school 11 days earlier than those not treated with antibiotics.

(Source:  https://www.livescience.com/63699-appendicitis-antibiotics.html)

FOR MORE INFORMATION ON THIS REPORT, PLEASE CONTACT:

BRIAN DONOHUE

BDONOHUE@UW.EDU

206.543.7856

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Marjorie Bekaert Thomas at mthomas@ivanhoe.com

Doctor Q and A

Read the entire Doctor Q&A for Giana Davidson, MD, MPH, associate professor of surgery

Read the entire Q&A