New research reveals how ADHD sparks extraordinary creativity-Click HereThis experimental “super vaccine” stopped cancer cold in the lab-Click HereScientists discover brain circuit that can switch off chronic pain-Click HereScientists unlock nature’s secret to a cancer-fighting molecule-Click HereScientists shocked as birds soaked in “forever chemicals” still thrive-Click HereCommon medications may secretly rewire your gut for years-Click HereNanotech transforms vinegar into a lifesaving superbug killer-Click HereScientists find brain circuit that traps alcohol users in the vicious cycle of addiction-Click HereScientists finally reveal what’s behind long COVID’s mysterious brain fog-Click HereA psychedelic surprise: DMT helps the brain heal after stroke-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Preventing Nausea in Young Cancer Patients – In-Depth Doctor’s Interview

0

Lexa Walsh, MD, MSPH, a Pediatric Oncologist at Phoenix Children’s Hospital talks about the CINV Dashboard and how its making a difference in patients’ lives.

Interview conducted by Ivanhoe Broadcast News in September 2019.

The idea of creating the dashboard came from you. How did that come about?

WALSH: I joined the faculty about two and a half years ago and I started taking care of patients on the floor. I have an interest in supportive care in oncology and so I was trying to update our protocol for anti emetics or medications for the prevention of nausea and vomiting. I was working with this one patient and she was getting very highly emetogenic chemotherapy and was having a lot of problems with it. So I had adjusted her regimen and it really was working well for her and then she came in the next time for her second cycle of chemotherapy and I just happened to see the dad in the hallway and  he was crying. He said “I’m so upset. The first cycle of the treatment you adjusted worked great, but nobody knew what worked and she vomited the whole cycle again”. And so then I went to IT. I had something really simple in mind of an alert or something to notify us of the regimen that worked, and it kind of mushroomed into this bigger project, looking at nausea and vomiting for all of our patients.

Just helping this one little girl launched a whole project.

WALSH: Yes.

What kind of difference is it making?

WALSH: Well I’ve noticed a huge difference since we’ve started the dashboard. And right now we’re collecting data to get more numbers of how it’s actually helping. But I really feel like our providers are all really tuned to giving the appropriate anti emetic regimen. It’s not something that providers always thought of, I think, because it’s just in addition to all the complicated things that they’re doing all day. But we kind of take that responsibility away from them and there’s a group of us who review the dashboard every day, and make sure that the right combination of drugs is ordered. And I’ve noticed huge differences, it’s much rarer now that patients are struggling with nausea and vomiting their whole admission.

The part I like about it is the multiple input. If you could talk a little bit about the benefits of that.

WALSH: It’s been a whole process to try and figure out the best way because nobody had really done something like this. And I think it’s an example of something I think that’s really interesting. We have all this data of what we should do but it doesn’t get to the patient very often. And so that gap – we’re trying to close using this project, but I think it’s a good example of how we might be able to do that with other things too because we spend millions and millions of dollars trying to figure out what’s the best thing to do and then we just don’t do it for a number of different reasons. And it’s not often what you think. It’s not that the providers don’t want to do it, it’s just that they’ve forgotten. It’s as easy as just prompting them to do the right thing and then it gets done a lot more frequently.

Is this system complicated or is it easy? I know it has a lot of information for providers.

WALSH: Yeah. And not all providers look at it. There’s a core group of us to make sure we look at it every day, but it’s available as a resource for all providers. The families don’t have access to it yet, but that may be something in the future. But one thing that we’ve added more recently is a nausea scale actually so that nurses are asking the patients, how are you feeling? Are you feeling nauseous? So we’re not just relying on vomiting. So the dashboard is now collecting vomiting and nausea, which is a unique thing to do.

It gives the kids a little bit of power too.

WALSH: Exactly. And then there’s a feedback so the nurse has to call the doctor if it’s above a certain level so that the patients can get medications if they need them instead of just feeling miserable all day, it’s more of a direct contact.

And I would think that because it’s stressful for everybody, I have to imagine providers too, when a child is throwing up and so sick and crying. This has to help with that too.

WALSH: Yeah, I think so. Something we know from the literature is the second most disturbing symptom from our families is nausea and vomiting, more than almost any other symptom. Families just really hate it. They hate seeing their children suffering. We have these great treatments. We also have to provide good supportive care so the patients aren’t miserable when we’re giving them the treatments.

What’s number one?

WALSH: I think it’s fatigue actually.

What haven’t I asked about the system that we should include in the story?

WALSH: It takes information from the nurses, from the medical record, from the pharmacy data and pulls it all together so you can look at it at one time. So it’s unique. It makes a more complicated system a little bit easier to understand.

You think this is something that will spread to other hospitals?

WALSH: We’re in talks with other hospitals. I think we might do that. I think there’s a lot of benefit in the data too. We have more numbers because a lot of the studies that have been done for these medications just use 20 or 30 patients. But we have hundreds of patients we can pull data from so that’s going to be really powerful too.

Right now you’re sharing data and sharing potentially ideas on how to strut the dashboard. 

WALSH: We’ve presented it to national conferences and other places are interested, but we’re sort of in the preliminary stages of that right now.

And how long ago did it go in online?

WALSH: A year. We’ve been using it for about a year.

END OF INTERVIEW

This information is intended for additional research purposes only. It is not to be used as a prescription or advice from Ivanhoe Broadcast News, Inc. or any medical professional interviewed. Ivanhoe Broadcast News, Inc. assumes no responsibility for the depth or accuracy of physician statements. Procedures or medicines apply to different people and medical factors; always consult your physician on medical matters.

If you would like more information, please contact:

Elaina Steingard

602-933-0824

esteingard@phoenixchildrens.com

Sign up for a free weekly e-mail on Medical Breakthroughs called First to Know by clicking here