Alzheimer’s might be powered by a broken sleep-wake cycle-Click HereBreakthrough blood test finally confirms Chronic Fatigue Syndrome-Click HereGum disease may quietly damage the brain, scientists warn-Click HereScientists reverse Alzheimer’s in mice with groundbreaking nanotech-Click HereIt sounds creepy, but these scientific breakthroughs could save lives-Click HereYour pumpkin might be hiding a toxic secret-Click HereA revolutionary DNA search engine is speeding up genetic discovery-Click HereWhy women live longer than men, explained by evolution-Click HereBananas could be ruining your smoothie’s health benefits-Click HereThis easy daily habit cuts heart risk by two thirds-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Hyperbaric Chamber Reverses CO Poisoning – In-Depth Doctor’s Interview

0

Surbhi Jain, MD, from AdventHealth, talks about Carbon Monoxide poisoning.

Interview conducted by Ivanhoe Broadcast News in January 2019.

Can you tell us how dangerous that can be? And elaborate a little bit on that.

Surbhi: Carbon monoxide is a deadly, poisonous gas that is odorless, colorless, and invisible. Specifically, in poorly ventilated systems, it is the main byproduct of any carbon-related material that is burning or has incomplete combustion. It floats and spreads around in our homes, workplaces, cars, and has a unique toxic component that can cause irreversible damage to our body. This is why it’s called the silent killer, but thankfully the spread of this gas can be easily stopped.

How does somebody know that they even have carbon monoxide poisoning?

Surbhi: That’s a very good question. Most of the time, people don’t realize that they are accumulating carbon monoxide in their body. When carbon monoxide levels are low, people may experience flu-like symptoms such as headaches, confusion, malaise, nausea and even vomiting. However, when levels are too high, some internal organs may experience symptoms, such as neurological problems, cardiac problems, chest pain, and in some cases, the patient may present himself or herself to the ER with an MI. Therefore if someone, who has been exposed to the burning of carbon based materials in a poorly ventilated environment exhibits flu-like symptoms or a change in behavior, it is likely that carbon monoxide is a cause.

Tell us a little bit about how it can be treated

Surbhi: First and foremost, if carbon monoxide is suspected, immediately remove the patient from the potential source and bring them to fresh, open air to allow them to breathe. If the person is unresponsive, faces trouble in breathing, or has low blood pressure, phone 9-11 and shut down all appliances in the building. Then, without harming yourself, evacuate as many people in the building, starting with elderly people or children under the age of 5. Bring them to the E.R. so that they can be stabilized and treated.

How does the hyperbaric oxygenator work?

Surbhi: The treatment of carbon monoxide poisoning is to supply normal oxygen, which is very helpful in accelerating the elimination of carbon monoxide in the body. However, in some cases, patients may face more severe symptoms, especially cognitive, which may occur over a period of time after acute exposure. It may take a week to 14 days for the symptoms to appear, and in those cases, hyperbaric oxygen therapy can extremely helpful. Not only does it serve as a potential lifesaver, but it can also work on improving other neurological functions and mechanisms that were disturbed by carbon monoxide.

And how does it work?

Surbhi: Hyperbaric allows the patient to breath oxygen in a pressurized chamber. When the person is breathing 100% oxygen in a pressurizes system, it accelerates the elimination of carbon monoxide and interferes with the activation of white cells, which are in the blood and can be the source of oxidative injury from the carbon monoxide. Hyperbaric medicine serves to eliminate the hyperactivation of white blood cells. In brief, the hyperbaric acts upon the injury damage at the cellular level, thus aiding in the treatment of neurological symptoms in affected patients.

So is this good for somebody whose symptoms didn’t show up until two weeks later?

Surbhi: Right. It’s good especially in delayed cases, which we call subacute carbon monoxide poisoning. Here, the patient has a documented exposure to the carbon monoxide and may have been discharged from the E.R., but the neurological symptoms present after 7 to 10 days. Hyperbaric should be considered in relation to the intensity of the neurological symptoms. Another point to stress upon is the levels of carboxyhemoglobin. These are important in very acute situations where you measure these levels at the scene. But after a patient has been given some form of treatment, these levels only serve as an indicator or guide, but cannot dictate the following treatment decisions.

How common do you see common monoxide poisoning?

Surbhi: Over 40,000 patients a year present to the E.R. with carbon monoxide exposure, and about 450 to 500 patients die each year from the carbon monoxide poisoning. It is one of the leading toxic causes of death and half of the fatal poisoning deaths in our country are attributed to carbon monoxide poisoning. Recall that it is found in smoke inhalation, which is the main concerns in house fires, burning carbon-based materials, usage of propane-powered devices, or burning charcoal or wood in a poorly ventilated area. Children under the age of 5, elderly people, and pregnant females are more at risk of getting affected by carbon monoxide poisoning.

It’s 40,000 a year in the United States?

Surbhi: In the United States, around 40,000 patients are affected, and a very large number of these patients actually die from the accidental exposure as a result of a house fire, smoke inhalation, and suicide, too.

So how important is it to address this?

Surbhi: It is very important to address this, but it’s a simple job of people installing carbon monoxide detectors in addition to a smoke detector in their homes. It’s inexpensive and effective in detecting the levels of carbon monoxide in your house. Even low amounts of carbon monoxide would yield an alarm, whether it’s in broad daylight or in the middle of the night. This is one simple way that people can save themselves and their near and dear ones.

So any household items besides a car being left on in the garage? What’s the typical things in the house…

Surbhi: Anything gas-powered can emit carbon monoxide. However, gas leaks do not emit carbon monoxide; only gas powered systems that involve the combustion of the burning of gas can emit carbon monoxide.

If somebody’s like oh, we don’t have a gas powered anything in our house. Are they safer?

Surbhi: Yes. If they do not carry anything gas-powered, propane-powered, or anything similar and also don’t burn wood or charcoal in closed rooms, then they are safe. Also, if people don’t repair cars in enclosed garages, especially in cold conditions, they are safe. One important point to stress upon would be leaving cars on, as they bring a very deadly convenience. People tend to forget and ignorantly leave cars on in their garage. This is a major safety issue as the exhaust constantly spews gas into the house. Low levels of carbon monoxide would slowly get accumulated in your body, especially during sleep, as you are spending a long time in an unsafe environment. This is how carbon monoxide poisoning happens.

END OF INTERVIEW

This information is intended for additional research purposes only. It is not to be used as a prescription or advice from Ivanhoe Broadcast News, Inc. or any medical professional interviewed. Ivanhoe Broadcast News, Inc. assumes no responsibility for the depth or accuracy of physician statements. Procedures or medicines apply to different people and medical factors; always consult your physician on medical matters.

If you would like more information, please contact:

Ashley Jeffery

803-582-9648

ashley.jeffery@adventhealth.com

Sign up for a free weekly e-mail on Medical Breakthroughs called First to Know by clicking here.