Gum disease may quietly damage the brain, scientists warn-Click HereScientists reverse Alzheimer’s in mice with groundbreaking nanotech-Click HereIt sounds creepy, but these scientific breakthroughs could save lives-Click HereYour pumpkin might be hiding a toxic secret-Click HereA revolutionary DNA search engine is speeding up genetic discovery-Click HereWhy women live longer than men, explained by evolution-Click HereBananas could be ruining your smoothie’s health benefits-Click HereThis easy daily habit cuts heart risk by two thirds-Click HereWeight-loss drugs like Ozempic may also curb drug and alcohol addiction-Click HereLife expectancy gains have slowed sharply, study finds-Click HereSports concussions increase injury risk-Click HereUncovering a cellular process that leads to inflammation-Click HereNew study links contraceptive pills and depression-Click HereA short snout predisposes dogs to sleep apnea-Click HereBuilding a new vaccine arsenal to eradicate polio-Click HereThe Viking disease can be due to gene variants inherited from Neanderthals-Click HereQatar Omicron-wave study shows slow decline of natural immunity, rapid decline of vaccine immunity-Click HereMore than a quarter of people with asthma still over-using rescue inhalers, putting them at increased risk of severe attacks-Click hereProgress on early detection of Alzheimer’s disease-Click HereDried samples of saliva and fingertip blood are useful in monitoring responses to coronavirus vaccines-Click HereDietary fiber in the gut may help with skin allergies-Click HereResearchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer-Click HereDespite dire warnings, monarch butterfly numbers are solid-Click HereImmunotherapy may get a boost-Click HereArtificial intelligence reveals a never-before described 3D structure in rotavirus spike protein-Click HereRecurring brain tumors shaped by genetic evolution and microenvironment-Click HereCompound shows promise for minimizing erratic movements in Parkinson’s patients-Click HereConsuming fruit and vegetables and exercising can make you happier-Click HereCOVID-19 slows birth rate in US, Europe-Click HereLink between ADHD and dementia across generations-Click HerePreventing the long-term effects of traumatic brain injury-Click HereStudy details robust T-cell response to mRNA COVID-19 vaccines — a more durable source of protection-Click HereArtificial color-changing material that mimics chameleon skin can detect seafood freshness-Click HereNeural implant monitors multiple brain areas at once, provides new neuroscience insights-Click HereB cell activating factor possible key to hemophilia immune tolerance-Click HereMasks not enough to stop COVID-19’s spread without distancing, study finds-Click HereAI can detect COVID-19 in the lungs like a virtual physician, new study shows-Click HerePhase 1 human trials suggest breast cancer drug is safe, effective-Click HereRe-engineered enzyme could help reverse damage from spinal cord injury and stroke-Click HereWeight between young adulthood and midlife linked to early mortality-Click HereIncreased fertility for women with Neanderthal gene, study suggests-Click HereCoronavirus testing kits to be developed using RNA imaging technology-Click HereFacial expressions don’t tell the whole story of emotion-Click HereAcid reflux drug is a surprising candidate to curb preterm birth-Click HereTreating Gulf War Illness With FDA-Approved Antiviral Drugs-Click HereHeart patch could limit muscle damage in heart attack aftermath-Click HereA nap a day keeps high blood pressure at bay-Click HereIn small groups, people follow high-performing leaders-Click HereTick tock: Commitment readiness predicts relationship success-Click HereA comprehensive ‘parts list’ of the brain built from its components, the cells-Click HereResearchers confine mature cells to turn them into stem cells-Click HereNew tissue-imaging technology could enable real-time diagnostics, map cancer progression-Click HereEverything big data claims to know about you could be wrong-Click HerePsychedelic drugs promote neural plasticity in rats and flies-Click HereEducation linked to higher risk of short-sightedness-Click HereNew 3D printer can create complex biological tissues-Click HereThe creative brain is wired differently-Click HereWomen survive crises better than men-Click HerePrecise DNA editing made easy: New enzyme to rewrite the genome-Click HereFirst Time-Lapse Footage of Cell Activity During Limb RegenerationStudy Suggests Approach to Waking Patients After Surgery

Male Breast Cancer: Really?

0

TAMPA, Fla. (Ivanhoe Newswire) — Despite what most of us take for granted, women aren’t the only ones who should worry about breast cancer. It strikes men as well. Catching it early is critical, but most men don’t even consider they could have it, let alone watch for it.

Paul Dombroski pushed his body to the limit.

To reach the top.

Not only did he make it to the NFL, the former Buccaneer was a two-time player of the year for the Patriots … then breast cancer lined up against him.

“I was yawning, and I lifted my arm up and I ran my hand across my chest and I felt a lump and immediately I knew it was breast cancer,” Dombroski said.

He was shocked, but right.

“Now I’m going get a mammogram? So first thing I do with the tech is how do I get this into that,” continued Dombroski.

The tumor was detected and removed early – good news for Dombroski. But he still worries about other men.

“We can call it your chest, you can call it your pecks. They’re breasts,” explained Dombroski.

Nicole Figueredo, MD, Florida Hospital, says men’s breasts are built much the same way women’s are. In 2018, more than two thousand men will be diagnosed with invasive breast cancer.

“Unfortunately, a lot of men with breast masses fail to go to the physician. That leads to breast cancer in men being diagnosed at later stages,” Dr. Figueredo said.

Here’s what to watch for: a firm lump behind the nipple, an itchy scaly rash, any change in shape or size, an inward pulling of the nipple. Thanks to his vigilance and preparation, Dombroski can list professional football player and breast cancer survivor on his resume.

Dr. Figueredo says sometimes breast cancer in men could be confused with benign breast development due to hormone change. Treatment in men is similar to women. Dombroski is working with Dr. Figueredo to create a more unisex environment to avoid female stigmas that surround breast cancer.

Contributors to this news report include: Emily Gleason, Field Producer; Roque Correa, Editor; and Chris Tilley, Videographer.

Free weekly e-mail on Medical Breakthroughs from Ivanhoe. To sign up: http://www.ivanhoe.com/ftk

MALE BREAST CANCER: REALLY?

REPORT #2591

BACKGROUND: All people, whether male or female, are born with some breast cells and tissue. Even though males do not develop milk-producing breasts, a man’s breast cells and tissue can still develop cancer. Even so, male breast cancer is very rare. Less than one percent of all breast cancer cases develop in men, and only one in a thousand men will ever be diagnosed with breast cancer. Breast cancer in men is usually detected as a hard lump underneath the nipple and areola. Men carry a higher mortality than women do, primarily because awareness among men is less and they are less likely to assume a lump is breast cancer, which can cause a delay in seeking treatment. Of the men who develop breast cancer, the vast majority of those cases are Infiltrating Ductal Carcinoma (IDC), which means cells in or around the ducts begin to invade surrounding tissue. Very rarely, a man might be diagnosed with inflammatory breast cancer, or Paget disease, of the nipple.

(Source: https://www.nationalbreastcancer.org/male-breast-cancer)

 

GENETIC TESTING: Although treatment outcomes are very similar to women at the same stage of detection, a man diagnosed with breast cancer should also consider seeing a genetics counselor for a consultation. If a man tests positive for a defective gene (most commonly either BRCA1 or BRCA2) that can lead to a future diagnosis of breast cancer, then his children have a 50 percent chance of carrying the gene. In addition, a male child of a man with breast cancer who inherits the defective BRCA2 gene has approximately 6 percent chance of eventually developing breast cancer and just over 1 percent with BRCA1. A female child of a man with breast cancer who inherits the defective gene has a risk between 40 percent and 80 percent of eventually developing breast cancer. Men with a genetic predisposition to breast cancer are also at higher risk of getting prostate cancer at a younger age than usually diagnosed.

(Source: https://www.nationalbreastcancer.org/male-breast-cancer)

ADVANCEMENTS IN MALE BREAST CANCER: The rarity and lack of surveillance of male breast cancer makes it a difficult disease to study. However, Breast Cancer Research Foundation (BCRF) investigators are tackling this challenge with the International Male Breast Cancer Study (IMBCS). Led by BCRF investigators, Dr. Fatima Cardoso and Dr. Sharon Giordano, the IMBCS is the largest international study in male breast cancer ever conducted. Investigators reported that as in female breast cancer, most breast cancers in men require the hormone estrogen to grow. These cancers are called estrogen receptor (ER)-positive. Conversely, the HER2-positive type of breast cancer, which makes up about 25 percent of female breast cancers, occurs rarely in men. Triple negative breast cancer, a rare aggressive disease accounting for about 15 percent of female breast cancer, makes up less than one percent of male breast cancers. Despite most male breast cancers being driven by estrogen, the IMBCS researchers found that few male breast cancer patients receive the appropriate treatment for this form of the disease. Dr. Ben Park, BCRF investigator, explained that to precisely treat the disease, it is important to know the mutations driving its growth and survival. They are already seeing the success of this approach in female breast cancers with targeted therapies against tumor promoting pathways, such as HER2 and CDK4/6. Similarly, Dr. Park envisions a future where all cancers are matched for the mutations in the tumor, making it less important whether that cancer is in the breast, the lung or colon, or whether the patient is male or female.

(Source: https://www.bcrf.org/blog/male-breast-cancer-research-advancements-and-challenges)

* For More Information, Contact:

Ashley Jeffery – Communications Manager

ashley.jeffery@ahss.org

(803) 582-9648