Inconsistencies in Clinical Trial Reporting Raise Questions
(Ivanhoe Newswire) – A Yale School of Medicine study found 93 of 96 studies investigated had discrepancies between the results reported to clinicaltrials.gov and the published results.
Since 2007, the FDA has required all completed clinical trials to be registered through clinicaltrials.gov. But when researchers at the Yale School of Medicine examined 96 studies published between 2010 and 2011, they found all but three of the studies had at least one discrepancy between the results reported to clinicaltrials.gov and the results published in high-profile, peer reviewed journals such as the New England Journal of Medicine and Lancet.
"This study raises serious questions about the accuracy of results reporting in both clinical trial registries and publications, and the importance of consistent presentation of accurate results," senior author Joseph Ross, M.D., assistant professor of medicine and public health at Yale School of Medicine, was quoted as saying. "Fortunately, of the 96 trials studied, only six of the discordant results altered the interpretation of the trial. But there still needs to be greater efforts to ensure accurate reporting in the future."
For more information, go to: http://news.yale.edu/2014/03/11/discrepancies-clinical-trial-reporting-raise-questions-accuracy
SOURCE: Journal of the American Medical Association, March 2014
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