New Drug Combination for Hepatitis C
(Ivanhoe Newswire) –Hepatitis C is a viral infection. If left untreated, it can lead to severe and possibly fatal liver damage. Existing treatments involve a combination of drugs and can place a substantial burden on the patient and some don’t respond. However, researchers are now exploring new drug combinations that could offer hope to patients who are unresponsive.
Researchers at the Texas Liver Institute in San Antonia, Texas, USA, and Gilead Sciences, Inc., recruited 100 patients with genotype 1 hepatitis C virus who had either never been treated (60 patients), or who had been treated unsuccessfully using existing drugs (40 patients). All trial participants took a new combination pill consisting of the investigational drugs sofosbuvir and ledipasvir.
At the end of the study, nearly all (97 or 97 percent) of the patients had achieved a sustained virological response—essentially a functional cure for hepatitis C, where the virus is eliminated, and prevented from replicating.
For more information, go to: http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2813%2962121-2/fulltext?elsca1=TW&elsca2=socialmedia
SOURCE: Lancet, November 2013
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