Treatment of Melanoma Requires Multiple Drugs
(Ivanhoe Newswire) – Recent findings show that more than one prescription drug is need to cease the spread of melanoma cancer cells. As the cells advance, they eventually become more resistant to one single drug.
Researchers at The Wistar Institute found that melanomas were not only resistant to drugs in the MEK2 gene, but they were mutating. They found that a combination of three drugs interrupted the growth of the tumors. They also found a new target for melanoma therapy, S6K; a protein revealed in their study.
"Melanoma tumors are particularly adept at rewiring themselves so that anticancer drugs lose their effectiveness, and we must continue to outthink the disease in order to block off all points at which it can evade therapy," Dr. Jessie Villanueva, Ph.D., assistant professor in Wistar's NCI-designated Cancer Center and member of The Wistar Institute Melanoma Research Center was quoted saying.
For more information, go to: http://www.wistar.org/news-and-media/press-releases/Villanueva_CellReports
SOURCE: Cell Reports, September 2013
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