Stomach Bacteria Turns off Immune's Defenses
(Ivanhoe Newswire) -- Helicobacter pylori is a bacterium that establishes a life-long stomach infection in humans, which in some cases can lead to duodenal ulcers or stomach cancer.
Researchers from the University of Nottingham have shown that H. pylori is able to suppress the body's normal production of “human beta defensin 1” (hβD1), an antimicrobial factor present in the stomach lining that helps prevent bacterial infection. By collecting stomach tissue biopsies from 54 patients at the Queens Medical Centre, Nottingham, the team showed that patients infected with H. pylori had ten times less hβD1 than uninfected patients. Those with the lowest amount of hβD1 had the most bacteria present in their stomach lining.
For more information go to: http://www.sgm.ac.uk/en/media_centre/society-news.cfm/stomach-bacteria-switch-off-human-immune-defences-to-cause-disease
SOURCE: Society for General Microbiology, September 2013
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