Genetic Variant links Coronary Heart Disease to Diabetics
(Ivanhoe Newswire)— A genetic variant found only in patients with type 2 diabetes may be a predictor of increased risk of coronary heart disease (CHD).
Researchers from Harvard University performed a genome-wide analysis on over 4,000 participants, which included control groups of patients who did not have diabetes. Over 2 million genetic variants were tested for an association with CHD. After a three-stage testing process, one genetic variant on one single chromosome was consistently associated with CHD. The variant was not present in the participants who did not have type 2 diabetes. The related chromosome is associated with the metabolism of glutamic acid.
For more information, go to: http://media.jamanetwork.com/news-item/genetic-variant-significantly-associated-with-increased-coronary-heart-disease-risk-in-individuals-with-type-2-diabetes/
SOURCE: JAMA, August 2013
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