Disabling Single Enzyme can Stop Cancer Growth
(Ivanhoe Newswire) – Researchers have found disabling one key enzyme can help stop the growth of aggressive cancer cells.
A research team from the University of California, Berkeley, wanted to learn more about the relationship between cancer cells and ether lipids, groups of molecules including cholesterol and fatty acids that are also particularly high in malignant tumors. Researchers injected mice with cancer cells and found that disabling an enzyme associated with the formation of ether lipids greatly reduced the growth and aggressiveness of cancer cells. The belief is these findings can lead to more effective and focused cancer treatment in the future.
"Lipids have a variety of uses for cellular structure, but what we're showing with our study is that lipids can also send signals that fuel cancer growth," principal study investigator Daniel Nomura was quoted as saying. "After disabling the enzyme, the cancer cells were less able to move and invade."
For more information, go to: http://newscenter.berkeley.edu/2013/08/26/ether-lipid-enzyme-aggressive-cancer/
SOURCE: Proceedings of the National Academy of Sciences, August 2013
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