Genetic Associations for Gastrointestinal Condition in Infants
(Ivanhoe Newswire) – Researchers have identified a significant genetic marker for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition.
The genetic marker is a genome-wide significant locus, which is the place a gene occupies on a chromosome. Researchers from the Statens Serum Institut, Copenhagen, Denmark, used three different sets of data to confirm their findings. After identifying five of the most significant loci from data provided by a Genome Project, they tested the loci against three sets of data from Sweden, Denmark, and the United States. They found one locus in particular was prevalent throughout the samples. Overall the study examined nearly 7,500 individual samples.
Their data also showed a potential relationship between neonatal levels of circulating cholesterol and a potential risk of IHPS.
For more information, go to: http://media.jamanetwork.com/news-item/study-examines-genetic-associations-for-gastrointestinal-condition-in-infants/
SOURCE: Journal of the American Medical Association, August 2013
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