Aging Gene Link to Blood Cancer
(Ivanhoe Newswire) -- Scientists at The Institute of Cancer Research in London have discovered a gene, which helps control the aging process by acting as a cell's internal clock, has been linked to myeloma.
The team found new markers by comparing the genetic make-up of a total of 4,692 myeloma patients with DNA from 10,990 people without the disease. The researchers discovered that one of the genetic marker was linked to a gene called TERC, which regulates the length of the telomere “caps” on the ends of DNA. In healthy cells these caps erode over time, causing tissues to age, but some cancer cells seem able to ignore the ageing trigger in order to keep on dividing. If further studies confirm the link, TERC could be a target for future myeloma treatments.
For more information go to: http://www.icr.ac.uk/press/press_archive/press_releases_2013/23948.shtml
SOURCE: Nature Genetics, August 2013
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