New Way to Detect Cancer
(Ivanhoe Newswire) -- DNA errors created during DNA replication can lead to many forms of cancer, including colorectal cancer, but a unique new study led by University of Kentucky Markey Cancer Center researchers Guo-Min Li and Libya Gu reveals a novel mechanism that explains the root cause of some forms of colorectal cancers.
The study found that an abnormal histone protein modification impairs a DNA repair machinery that controls cancer development, resulting in a potential new way of detecting these types of colorectal cancers. It represents for the first time that epigenetic histone marks regulate the genome maintenance system. "This study provides new clues to cancer etiology, that is, from the classical genetic defects to abnormal epigenetic modifications in the future," Dr. Li was quoted as saying.
For more information go to: http://uknow.uky.edu/content/uk-study-shows-potential-new-way-detect-colorectal-and-other-cancers#.UXqBwkZbNbc.mailto
SOURCE: CELL, May 2013
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