Multiple Sclerosis and Atrophy
(Ivanhoe Newswire) – Researchers have found that MRI measurements of atrophy in an important area of the brain is an accurate predictor of multiple sclerosis (MS). They believe this discovery offers an improvement over current methods for evaluating patients at risk for MS.
The researchers used contrast-enhanced MRI for initial assessment of 216 clinically isolated syndrome (CIS) patients. Over two years, 92 of 216 patients, or 42.6 percent, converted to clinically definite MS. Decreases in thalamic volume and increase in lateral ventricle volumes were the only MRI measures independently associated with the development of clinically definite MS.
Their findings suggest that measurement of thalamic atrophy and an increase in ventricular size may help identify patients at high risk for conversion to clinically definite MS in future clinical trials involving CIS patients.
SOURCE: Radiology Journal, April 2013