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Diabetes Channel
Reported March 22, 2013

"Weighing In" on a Diabetes Discovery

GAINESVILLE, Fla. (Ivanhoe Newswire) -- There’s no cure and the cause is unknown. Up to three million Americans have type-one diabetes. It’s already known people with it have smaller pancreases, but a new discovery could carry a lot of weight when it comes to beating diabetes.

“I was like so tired and sick,” Jordan Perkins, who has type 1 diabetes, told Ivanhoe.

Jordan Perkins was only eight when she found out.

“It was a surprise that I had diabetes,” Perkins said.

To manage her type 1 diabetes, “I have to do shots and prick my finger,” five times a day, Perkins explained.

Jordan’s pancreas stopped making insulin when her immune system started attacking these insulin-producing beta cells. Now, we could be closer to finding out why that happens.

“It is a first of its kind,” Dr. Martha Campbell-Thompson, Professor of Pathology at the University of Florida, told Ivanhoe.

In this lab, Dr. Martha Campbell-Thompson’s team weighed pancreases from 164 deceased donors. The pathologist found pancreases at high risk for developing type-one diabetes, weighed 25 percent less than normal ones.

“This implies that even before one becomes diabetic, you may have fewer insulin producing beta cells. It could be happening many years before signs of diabetes occur,” Dr. Campbell-Thompson said.

She wants to work with ongoing diabetes studies to determine if people with varying degrees of diabetes risk also have smaller pancreases.

“Measure their pancreas volume using something like as simple and safe as ultrasound,” Dr. Campbell-Thompson said.

Finding patterns in pancreas weight could help predict risk, treat the disease, and maybe even prevent kids like Jordan from ever having to deal with diabetes.

Thompson believes it will be relatively easy to add an ultrasound or MRI test to current diabetes studies to measure pancreas size. In the meantime, a pilot study at the University of Florida to further examine the findings is in the works. Thompson hopes it will eventually expand to sites across the country.  MORE.

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Click here for additional research on "Weighing In" on a Diabetes Discovery

Click here for Ivanhoe's full-length interview with Dr. Martha Campbell-Thompson

If this story or any other Ivanhoe story has impacted your life or prompted you or someone you know to seek or change treatments, please let us know by contacting Andrew Mcintosh at amcintosh@ivanhoe.com

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