Medical Breakthroughs Reported by Click here to go to the homepage.
Be the First to Know. Click here to subscribe FREE!
Search Reports: Use quotation marks around your multi-word search terms in the box below to perform search of
Advances in health and medicine.Use " marks around search terms
What's New
News Flash
  Alternative Health
Asthma & Allergies
Breast Cancer
Cardiovascular Health
Children's Health
Dental Health
Fertility & Pregnancy
Men's Health
Mental Health
Multiple Sclerosis
Neurological Disorders
Nutrition & Wellness
Pet Health
Seniors' Health
Sports Medicine
Women's Health
Advances in health and medicine.
Click here to sign up for Medical Alerts!
Click below to access other news from Ivanhoe Broadcast News.
  Click here to get Ivanhoe's Medical Headline RSS feed Click here to listen to Ivanhoe's Medical Podcasts
Useful Links
Play It Again, Please
E-Mail a Friend
Order Books Online
Inside Science
Smart Woman
Advances in health and medicine.
Smart Woman Home
Click here to read the story
Click here to read the story
Click here to read the story
Smart Woman Home
Advances in health and medicine.
Click below to learn about Ivanhoe.
About Us
Contact Us
Ivanhoe FAQ
Our TV Partners
Travel Calendar
Advances in health and medicine.
Ivanhoe celebrates 20 years of medical news reporting reaching nearly 80 million TV households each week. Click here to learn more...
Advances in health and medicine.
Marjorie Bekaert Thomas
Advances in health and medicine.
General Health Channel
Reported February 12, 2013

Teaching an Old Drug New Tricks


(Ivanhoe Newswire) – It’s great finding a new purpose for old things, especially when it comes to medicine. 
According to a new study, a drug used to treat asthma and canker sores may also help to treat diabetes and obesity. 
In the study genetic and dietary-induced obese mice were given the drug amlexanox, different forms of which are used to treat asthma and canker sores. After taking the medication the mice began to lose weight and metabolic problems associated with obesity such as diabetes and fatty liver began to improve. 
"Amlexanox seems to tweak the metabolic response to excessive calorie storage in mice,” Alan Saltiel, the Mary Sue Coleman director of the Life Sciences Institute was quoted as saying. 
Why exactly this drug aids weight loss and reverses metabolic problems has to do with two genes, IKKE and TBK1. Expression of these genes can cause individuals’ metabolisms to slow down, leading to obesity and other weight-related health problems. The link between the two genes and obesity was first discovered by Saltiel in 2009. 
Attempting to find something that would inhibit IKKE and TBK1, Saltiel came across amlexanox and found his answer.  
"By releasing the brake, amlexanox seems to free the metabolic system to burn more, and possibly store less, energy,” Saltiel was quoted as saying. 
But don’t get too excited about losing weight with amlexanox just yet. It still needs to be seen if the drug will have the same effect on obese and diabetic humans as it did on the study mice. 
Source: Nature Medicine,  February 2013
Related Articles in Latest Medical News:

[ Back to General Health Channel Home ]

Stay up to date on General Health. We can notify you every time there is a medical breakthrough. Click here to sign up.
Most Recent Videos
Your Baby DVD
What Every Pregnant Woman Should Know

Happier Woman DVD
25 ways to reduce stress

Forever Young DVD
25 ways to lose 10 years

Feel Good Again DVD
25 ways to STOP THE PAIN

If a treatment you read about here helps you, let us know...Click here!!

Follow Us On:

Click here to go to Ivanhoe's Twitter page Click here to go to Ivanhoe's Facebook page Click here to go to Ivanhoe's YouTube page

Do you know if you are height-weight proportional?

Find out your Body Mass Index (BMI).

Click Here


How safe are your dietary supplements?

Click here to find out with the FDA's list of supplements and drug interactions.

Home | What's New | News Flash | Search/Latest Medical News | E-Mail Medical Alerts!
Ivanhoe FAQ | Privacy Policy | Our TV Partners | Awards | Useful Links | Play It Again, Please
RSS Feeds | Advertising/Sponsorships | Content Syndication | Reprints

Advances in health and medicine.
Copyright © 2016 Ivanhoe Broadcast News, Inc.
2745 West Fairbanks Avenue
Winter Park, Florida 32789
(407) 740-0789

P.O. Box 865
Orlando, Florida 32802

Premium Content in Latest Medical News Denotes Premium Content in Latest Medical News