Medical Breakthroughs Reported by Ivanhoe.com. Click here to go to the homepage.
Be the First to Know. Click here to subscribe FREE!
Search Reports: Use quotation marks around your multi-word search terms in the box below to perform search of Ivanhoe.com.
Advances in health and medicine.Use " marks around search terms
 
What's New
News Flash
Discussion
healthchannelnews
  Alternative Health
Arthritis
Asthma & Allergies
Autism
Breast Cancer
Cancer
Cardiovascular Health
Children's Health
Dental Health
Diabetes
Fertility & Pregnancy
Men's Health
Mental Health
Multiple Sclerosis
Neurological Disorders
Nutrition & Wellness
Orthopedics
Pet Health
Robotics
Seniors' Health
Sports Medicine
Vision
Women's Health
Advances in health and medicine.
Click here to sign up for Medical Alerts!
Click below to access other news from Ivanhoe Broadcast News.
  Click here to get Ivanhoe's Medical Headline RSS feed Click here to listen to Ivanhoe's Medical Podcasts
Useful Links
Play It Again, Please
E-Mail a Friend
Order Books Online
Inside Science
Smart Woman
Advances in health and medicine.
Smart Woman Home
Click here to read the story
Click here to read the story
Click here to read the story
Smart Woman Home
Advances in health and medicine.
Click below to learn about Ivanhoe.
  Awards
About Us
Contact Us
Employment
Feedback
Ivanhoe FAQ
Our TV Partners
Travel Calendar
Advances in health and medicine.
Ivanhoe celebrates 20 years of medical news reporting reaching nearly 80 million TV households each week. Click here to learn more...
Advances in health and medicine.
Marjorie Bekaert Thomas
Publisher/President
Advances in health and medicine.
Advertisement
General Health Channel
Reported September 22, 2011

Shark Compound Treats Viruses?

(Ivanhoe Newswire) -- A compound that was initially isolated from sharks may serve as an antiviral treatment, according to a new study.

The compound -- known as squalamine -- has been studied in human clinical trials for treating cancer and eye disorders. In both lab and animal studies, the compound showed antiviral activity against human pathogens.

"To realize that squalamine potentially has broad antiviral properties is immensely exciting, especially since we already know so much from ongoing studies about its behavior in people," the study's lead investigator, Michael Zasloff, M.D., Ph.D., professor of surgery and pediatrics at Georgetown University Medical Center and scientific director of the Georgetown Transplant Institute, was quoted as saying.

Dr. Zasloff first discovered squalamine in 1993 when he was searching for antibacterial agents and became interested in sharks because of their immune systems. Since 1995, squalamine has been synthesized in the lab -- a process that does not involve the use of any natural shark tissue.

"I believe squalamine is one of a family of related compounds that protects sharks and some other 'primitive' ocean vertebrates, such as the sea lamprey, from viruses," Dr. Zasloff said.

"Squalamine appears to protect against viruses that attack the liver and blood tissues, and other similar compounds that we know exist in the shark likely protect against respiratory viral infections, and so on."

Dr. Zasloff sent the compound to researchers around the country. In tissue culture studies, squalamine was shown to inhibit the infection of human blood vessel cells by the dengue virus and human liver cells infected with hepatitis B and D, which can cause liver failure and cancer. In animal studies, researchers found squalamine controlled infections of yellow fever, Eastern equine encephalitis virus, and murine cytomegalovirus, and in some cases, cured the animals.

"We have not yet optimized squalamine dosing in any of the animal models we have studied, and as yet, we do not know the maximum protective or therapeutic benefit that can be achieved in these systems," Zasloff said."But we are sufficiently convinced of the promise of squalamine as an antiviral agent that we intend to take this compound into humans. It is clearly a promising drug, and is unlike, in its mechanism of action and chemical structure, any other substance currently being investigated to treat viral infections."

SOURCE: Proceedings of the National Academy of Sciences, September 19, 2011

To Receive Med Alerts all year click here.

Related Articles in Latest Medical News:

[ Back to General Health Channel Home ]

MEDICAL ALERT!
Stay up to date on General Health. We can notify you every time there is a medical breakthrough. Click here to sign up.
EDITOR'S CHOICE
Most Recent Videos
Your Baby DVD
What Every Pregnant Woman Should Know

Happier Woman DVD
25 ways to reduce stress

Forever Young DVD
25 ways to lose 10 years

Feel Good Again DVD
25 ways to STOP THE PAIN

If a treatment you read about here helps you, let us know...Click here!!

Follow Us On:

Click here to go to Ivanhoe's Twitter page Click here to go to Ivanhoe's Facebook page Click here to go to Ivanhoe's YouTube page

Scale
Do you know if you are height-weight proportional?

Find out your Body Mass Index (BMI).

Click Here

Advertisement

How safe are your dietary supplements?

Click here to find out with the FDA's list of supplements and drug interactions.

Home | What's New | News Flash | Search/Latest Medical News | E-Mail Medical Alerts!
Ivanhoe FAQ | Privacy Policy | Our TV Partners | Awards | Useful Links | Play It Again, Please
RSS Feeds | Advertising/Sponsorships | Content Syndication | Reprints

Advances in health and medicine.
webdoctor@ivanhoe.com
Copyright © 2014 Ivanhoe Broadcast News, Inc.
2745 West Fairbanks Avenue
Winter Park, Florida 32789
(407) 740-0789

P.O. Box 865
Orlando, Florida 32802

Premium Content in Latest Medical News Denotes Premium Content in Latest Medical News